Abstract
Mast cell tumour (MCT) is the second most frequent malignant neoplasm in dogs. The pathogenesis of the disease is still unclear, however, its prevalence in certain breeds presupposes a genetic pathway for its development. One of the pathways of maintenance and genetic repair of cells is the Theta-Mediated End Joining (TMEJ), being the main enzyme the DNA polymerase ¸, encoded by the POLQ …