CV Lattes
ORCID
Abstract
Doxorubicin is a widely used chemotherapy drug, but its use may be limited due to side effects, such as cardiotoxicity, which can lead to heart failure, a chronic and irreversible disease, with high morbidity and mortality rates. The activation of matrix metalloproteinases, which are enzymes responsible for the degradation of the extracellular matrix, appear to be involved in the pathophy…