Abstract
The Goto-Kakizaki (GK) rats are widely recognized for developing insulin resistance (IR), resulting in basal hyperglycemia and, consequently, the pathogenesis of type 2 diabetes mellitus (T2DM). The development of this pathology may be related to the gut microbiome of these animals. Studies have shown differences in the composition of gut microbiota between GK and Wistar rats, which may b…