Abstract
Inflammasomes are multimeric, proteic complexes formed by intracellular receptors of NLF family, adaptor protein ASC and Caspase-1. Upon activation, it leads to cleavage and functional activation of interleukins IL-1¿, IL-18 and pore forming protein gasdermin D (GSDMD), causing inflammatory cell death, named pyroptosis. Inflammasomes require two signals for activation: the first signal, o…