Abstract
Most cases of differentiated thyroid cancer (DTC) have a favorable prognosis; however, approximately 10% progress with metastasis and may not respond to conventional radioiodine therapy (RAI). Poorly differentiated cancer and anaplastic thyroid carcinoma (ATC) are the rarest types (1-2%) and the most aggressive, highly undifferentiated, radioiodine-refractory, resistant to chemotherapy or…