Abstract
Introduction: Malignant neoplasms of the hepatic and biliopancreatic systems, represented by hepatocellular carcinoma (HCC), cholangiocarcinoma (CCA), and pancreatic ductal adenocarcinoma (PDAC), compromise the functionality of the liver, bile ducts, and pancreas, accounting for the third leading cause of cancer-related deaths worldwide. The decisive role of the inflammatory process in tu…