Abstract
Immunotherapies using chimeric antigen receptor (CAR) anti-CD19 T cells have demonstrated surprising clinical efficacy against B-cell malignancies. However, the treatment of relapsed and refractory (R/R) acute myeloid leukemia (AML) has low cure rates. Despite the encouraging results with CAR-T therapy, the number of patients who relapse after treatment is worrying, with antigen loss bein…