Abstract
The antitumor efficiency of alpha-galactosylceramide (aGC)depends both on IFN-gamma production and on cytotoxic pathways such as FasL and NKG2D. Recent data from our group show that glucose metabolism is a critical process for IFN-gamma production by iNKT lymphocytes when stimulated with aGC. Therefore, it is reasonable to assume that in a glucose-deprived environment-commonly observed du…