Abstract
The 70 kDa heat shock protein, HSP70, is a central molecular chaperone in proteostasis, whose expression is induced by different types of stress including hypoxia. However, human microvascular and human umbilical vein endothelial cells subjected to hypoxia do not induce the expression of HSP70. Furthermore, we showed that there is a reduction in the formation of the HSP90 dimer and of mac…