CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Coordenadoria de Controle de Doenças (CCD). Instituto Adolfo Lutz (IAL) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduate at Biological Sciences from Faculdade de Ciências Médicas e Biológicas de Botucatu Unesp (1976), graduate at Biological Sciences (Bachelor) from Faculdade de Ciências Médicas e Biológicas de Botucatu Unesp (1977), master's at Ciências Microbiologia from Universidade de São Paulo (1997) and ph.d. at Sciences (MicrobiologY) from Universidade de São Paulo (2000). Nowadays is a scientific researcher at Adolfo Lutz Institute. Has experience in Microbiology, focusing on Medical Microbiology, acting on the following subjects: Gram-negative bacilli nonfermenting, such as, Stenotrophomonas maltophilia, cystic fibrosis, Pseudomonas aeruginosa and Burkholderia cepacia, enterobacteria, microbial resistance and molecular epidemiology. Master and Doctoral's advisor at Post-graduation course from Diseases Control Center, in the area of Laboratory Research in Public Health. (Source: Lattes Curriculum)
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The first isolation of KPC-producing K. pneumoniae in Brazil was in 2005, rapidly disseminating to several hospitals in São Paulo State, as well as other States. The aim of this study is to evaluate the genetic diversity of KPC-producing K. pneumoniae isolates from several hospitals of São Paulo State to detect intra and inter-hospital clonal dissemination. Approximately 100 K. pneumoniae…
Klebsiella pneumoniae which produces extended-spectrum B-lactamase (ESBL) are frequent1y involved in nosocomial infections in intensive care units (ICUs) inc1uding neonatal ICUs (NICUs). ESBL confer resistance to all penicillins, broad-spectrum cephalosporins and aztreonam. CTX-M-2 is the most prevalent ESBL type in Brazil. Carbapenems are the treatment of choice for serious infections ca…
KPC-2 producing Klebsiella pneumoniae belonging to ST437 is considered predominant in Brazil. This ST has also been reported in the water of major rivers of Sao Paulo City, rivers Tiete and Pinheiros, demonstrating how these microorganisms can get out the hospital and come to the environment facilitating their spread. This leads to a concern about how the treatment and dumping of such eff…
Klebsiella pneumoniae producing extended spectrum beta-lactamases(ESBL) and KPC are often involved in health care associated infections (HAI). Plasmids responsible for producing these enzymes may carry genes responsable for resistance to aminoglycosides. Recently, a new mechanism for resistance to aminoglycosides was detected in Gram-negative bacteria, 16S rRNA methyltransferases, which c…
K. pneumoniae producing extended-spectrum b-lactamases (ESBLs) are frequently involved in hospital infections in intensive care unit (ICU), including neonatal ICU. ESBLs are capable of hydrolyzing all penicillins, cephalosporins and aztreonam, and the most prevalent ESBL in Brazil is CTX-M-2. Carbapenems are considered the agents of choice for treatment of infections caused by ESBL-produc…
(Only some records are available in English at this moment)
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