CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Assistant Professor at the Department of Physiology and Biophysics of the Institute of Biological Sciences at UFMG, with a research focused on Functional Aspects, Neuromodulation, and Disorders Affecting Cardiorespiratory Control. Holds a degree in Radiology Technology from the University of Franca (2007), a master's degree in Morpho-functional Sciences from the University of São Paulo (2011), and a doctorate in Sciences with an emphasis in Human Physiology from the Graduate Program in Human Physiology (ICB-USP) (2015), where he also completed a postdoctoral fellowship (2016-2022). He completed a visiting schollar program (2013) and a postdoctoral fellowship (2017) at the University of Connecticut, where he assumed the position of Postdoctoral Research Associate in 2022 and, between 2023 and 2024, served as a Research Assistant Professor in the Department of Physiology and Neurobiology (PNB-UCONN), coordinating research projects that evaluate respiratory alterations in models of Congenital Central Hypoventilation Syndrome and central and peripheral respiratory and cellular alterations in models of Autism. (Source: Lattes Curriculum)
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Neurons with chemosensory properties are specialized structures located in the central nervous system (CNS), which are able to detect changes in CO2 concentrations and plasma pH and promote appropriate adjustments in ventilation to restore blood gas homeostasis. Located near the ventrolateral surface of medulla oblongata, the retrotrapezoid nucleus (RTN) receives prominent role by fulfil …
The retrotrapezoid nucleus (RTN), which is located ventrally to the facial motor nucleus, very close to the ventrolateral medulla surface, represents the main cluster of cells with chemosensitive characteristics. These neurons are highly sensitive even to an increased CO2 partial pressure or a reduction in pH. In these conditions, the RTN neurons leading to an increased respiratory activi…
The retrotrapezoid nucleus (RTN) contains neurons that regulate breathing in response to changes in tissue CO2/H+ (central chemoreceptors), increasing the inspiration and generating active expiration. Recently, a new rhythm structure breathing-related has been identified in the medulla, a cluster compose by neurons that co-expressing Glutamate and Acetylcholine which displays autonomous b…
Central chemoreception is the mechanism by which the brain regulates breathing in response to changes in tissue CO2/H+. A brainstem region called the retrotrapezoid nucleus (RTN) contains a population of CO2/H+-sensitive neurons that appears to function as an important chemoreceptor. Evidence also indicates that CO2-evoked ATP release from RTN astrocytes modulates activity of CO2/H+-sensi…
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