Francemilson Goulart da Silva

CV Lattes ORCID Google Scholar Citations

Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal)
Birthplace: Brazil

graduate at Enfermagem from Universidade do Oeste Paulista (2000), master's at Fisiologia Humana from Universidade de São Paulo (2003) and ph.d. at Physiology from Universidade de São Paulo (2008). Has experience in Physiology, focusing on Physiology, acting on the following subjects: cytoskeleton, thyroid hormone, actin, hormônio tiroideano and osteoprotegerina. (Source: Lattes Curriculum)

News published in Agência FAPESP Newsletter about the researcher

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Research grants

Completed (most recent)

Abstract
Fenofibrate (FF) and ezetimbe (EZ) treatments of dyslipidemia prevent cardiovascular diseases by decreasing serum cholesterol (TC) and triacylglycerols (TAG) levels. Despite of FF, a PPAR-a agonist, increases lipids oxidation and EZ inhibits intestinal cholesterol uptake, it is not clear whether lipids absorption reduce after FF and EZ administration, which would directly impact the lipem…
Fibrates and ezetimibe effect on the jejunum: correlation of proteomic, molecular and functional findings with the improvement of obesity-induced hyperlipidemia, AP.R
Abstract
Although the mechanisms of the nutrients transport regulation across the intestinal epithelium are very important, few studies have addressed this issue. This call our attention considering some aspects of the contemporary world characterized by consumption of high-fat and high-carbohydrate diets, leading to an increase in obesity and its comorbidities, as cardiovascular diseases, diabete…
Repercussions of the high fat diet chronic intake on the mechanisms of nutrients transport of enterocytes: evaluation of the involvement of thyroid hormones in these processes, AP.R

Scholarships in Brazil

Completed (most recent)

Abstract
The prolonged consumption of a High-Fat Diet (HFD) is associated with the development of several diseases, such as Diabetes, Cancer, cardiovascular diseases, among others. In this scenario of HFD feeding and metabolic changes, we observed a reduction of gut nutrients transporters for carbohydrates (GLUT2), peptides (PEPT1) and lipids (FAT/CD36 and NPC1L1) in mice. The most abundant fatty …
Pro-inflammatory cytokines expression and their correlation to nutrient transporters and intestinal permeability in murine treated with fatty acids, BP.DR

Scholarships abroad

Completed (most recent)

Abstract
Ingestion of a high-fat diet (HFD) by mice can alter macronutrient transporters, intestinal permeability, and gut microbiota composition, which drive changes to nutrient absorption. The most abundant fatty acids (FA) in HFD are palmitic (PA), stearic (EA) and oleic (OA) acids, and the SFAs (PA and EA) are associated with the pro-inflammatory action via TLR/NF-º² in different tissues. Patt…
Determining how high-fat diet derived fatty acids and the gut microbiota interact to engage innate immunity via pattern recognition receptors, BE.EP.DR

Virtual Library in numbers * Updated data on August 16, 2025

Total / Available in English

2 / 2	Completed research grants
2 / 1	Completed scholarships in Brazil
1 / 1	Completed scholarships abroad
5 / 4	All research grants and scholarships

Associated processes

Most frequent collaborators in research granted by FAPESP

Keywords used by the researcher

Biological Sciences Physiology

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