Ricardo Mauricio Xavier Leão

• Abstract

  ATP-sensitive potassium channels (KATP) belong to the Kir6 channel family (Kir6.1 and Kir6.2 subunits), and traditionally link the energy state of the cell to the membrane potential. Its function is well characterized in pancreatic beta cells, participating in the secretion of insulin and in hypothalamic neurons that participate in the regulation of glycemia and energy metabolism, but the…

  ATP-sensitive potassium channels in the control of neuronal excitability, AP.R

• Abstract

  The world is increasingly a place where humans are exposed to high-intensity sounds. The most common problems associated with exposure to high noise levels are hearing loss, tinnitus (ringing in the ears)) and hyperacusis. Not all people exposed to high-intensity sounds develop tinnitus, which is also observed in experimental animals. The dorsal cochlear nucleus (DCN) is a region that ha…

  Changes during the development of ionic currents and neurotransmission of auditory neurons: effects of the acoustic environment, AP.R

• Abstract

  The limbic system is affected by sensory stimuli, including stimulation from the auditory system. Not only, neurons and synapses from regions like the hippocampus and the amygdala can be affected by auditory stimulation and some pathologies of the auditory system caused by acoustic trauma, as for example tinnitus, have a strong limbic component. Recently we demonstrated that chronic high-…

  High intensity sound stimulation and synaptic plasticity, AP.R

(Only some records are available in English at this moment)

• Electrophysiological, synaptic and molecular characterization of the neurons of the medial caudal Nidopallium, an area responsible for auditory processing in songbirds, BP.DR