Abstract
Androgens and estradiol (E2) are associated with diabetes mellitus and glucose intolerance. High levels of testosterone (T) free or bioavailability represent predictive factors for insulin resistance and Type 2 diabetes mellitus (T2DM) in women. Moreover, women with low levels of sex hormone binding globulin (SHBG) are also susceptible to developing type 2 diabetes. The Epigenetics has be…