CV Lattes
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Secretaria da Saúde (São Paulo - Estado). Instituto Butantan (Institutional affiliation from the last research proposal) Birthplace: Brazil
Under-graduation in Veterinary Medicine, Universidade de São Paulo (1987); under-graduation in Letters (Italian and Portuguese), Universidade de São Paulo (1998); under-graduation in Letters (Latin), Universidade de São Paulo (2007); MSc in Clinical Analyses, Universidade de São Paulo (1993); PhD in Physiology, Universidade de São Paulo (2002). I have experience in human and animal Hematology, acting on the following subjects: (1) hemostasis, blood coagulation, fibrinolysis and blood platelets; characterization of biological activities of animal venoms; envenomations by venomous animals. (Source: Lattes Curriculum)
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Bothrops jararaca snake venom (BjV) remarkably alters Hemostasis and Inflammation, but few studies have examined the interaction between these processes during envenomation, whose understanding is essential to improve the treatment of patients. Various toxins from BjV showing either pro- or anti-hemostatic activities induce bleeding in bitten patients, associated with the presence of thro…
The venom of the pit viper Bothrops jararaca (a species that inhabits from southern Bahia state in Brazil to Misiones province in Argentina) interferes in various biological systems in a complex and dynamic manner, leading to the rapid death of their natural preys. Among these biological systems, the hemostatic system is a pivotal target for snake venoms, and particularly B. jararaca veno…
(Only some records are available in English at this moment)
Snakebites caused by serpents of the genus Bothrops are a significant cause of morbidity and mortality in various regions of Latin America, including Brazil. The venom from these snakes is known for being rich in toxins and enzymes that can cause hemotoxic disturbances, impacting the coagulation process and increasing the risk of bleeding. Thrombocytopenia, a reduction in the count of cir…
Bites by Bothrops snakes, which induce disturbances that lead to mortality or morbidity of patients, are a major public health issue in Brazil. Envenomation by Bothrops jararaca snakes induces hemostatic alterations, such as thrombocytopenia, consumptive coagulopathy, and bleedings. Furthermore, it also produces a state of local and systemic inflammatory reaction, leading to activation of…
The activity of Bothrops jararaca venom is broad and complex on biologic systems of preys, showing pro- and anti-hemostatic features. Venom proteins may alter by various approaches the hemostatic systems. Several systemic manifestations are described during B. jararaca envenomation, and bleedings are the most conspicuous one. Systemic bleeding is multifactorial, and patients manifest cons…
Resumo do artigo que está sendo submetido à publicação no Journal of Thrombosis and Haemostasis, referente aos resultados obtidos pela aluna em sua dissertação de mestrado.The release of plasma tissue factor (TF) in bloodstream has never been demonstrated in snake envenomation, although it may aggravate the bleeding tendency. Aiming to investigate the contribution of venom metalloproteina…
(Only some records are available in English at this moment)
| 1 / 0 | Ongoing grants |
| 12 / 9 | Completed research grants |
| 1 / 1 | Ongoing scholarships in Brazil |
| 5 / 5 | Completed scholarships in Brazil |
| 1 / 0 | Completed scholarships abroad |
| 20 / 15 | All research grants and scholarships |
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