Abstract
The aim of the present study is to investigate the influence of neural histamine in learned helplessness, emotional memory and neurogenesis of mice. Therefore, animals should be subjected to the chronic variable stress (CVS) for 7 days. During that period, the treated animals Will receive systemic injections of imipramine (10 mg/kg) or L-histidine (200 and 500 mg/kg) by volume of 2 ml/kg.…