Abstract
Schistosoma mansoni, parasite responsible for schistosomiasis, a disease that affects about 300 million people worldwide, lacks the synthetic pathway of purines, depending entirely on the way to salvation for their supply of purine bases of these. The enzyme adenosine kinase (AK), hypoxanthine-guanine phosphoribosyltransferase (HGPRT), adenilosuccinato synthase (ADSS) and adenilosuccinato…