CV Lattes
Universidade Estadual de Campinas (UNICAMP). Centro de Hematologia e Hemoterapia (HEMOCENTRO) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Biomedicina from Centro Universitário Herminio Ometto de Araras (2008). (Source: Lattes Curriculum)
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Myelodysplastic syndromes (MDS)are a heterogeneous group of clonal hematopoietic disorders that display ineffective hematopoiesis. About a third of patients with MDS progress to AML. The microenvironment contributes to the regulation of self-renewal, maintenance, differentiation, proliferation and apoptosis of progenitor cells and when is abnormal can favor diseases development. Previous…
The myelodysplastic syndrome (MDS) is caused by a complex group of setbacks in hematopoietic stem cells and is characterized by cytopenia in peripheral blood. With the progression of the disease patients are at risk of developing acute myeloid leukemia (AML). Most patients with MDS and acute leukemia (AL) are resistant to treatment and between 10 to 20% of patients with acute leukemia hav…
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