CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Graduated in Biomedical Sciences from Universidade Cidade de São Paulo. During her undergraduate studies, she was a scientific initiation scholarship holder at the Laboratory of Molecular Biology and Functional Anatomy of the Institute of Biomedical Sciences of the University of São Paulo (ICB/USP), where she also completed her master's and doctorate degrees, under the supervision of Dr. Maria Luiza Barreto-Chaves. Her line of research focuses on the investigation of signaling pathways associated with cardiac hypertrophy in hyperthyroidism, with an emphasis on the renin-angiotensin system. In her postdoctoral studies, under the supervision of Dr. Gabriela Diniz, she explored the involvement of miR-22 in senescence and dysfunction of adipose tissue in the context of obesity. She has extensive experience in preclinical research, is an expert in cellular and molecular biology techniques and has extensive experience in cell culture. In recent years, she has worked as an academic manager of research projects in laboratories at ICB/USP. For contact: carolineantuneslino@gmail.com (Source: Lattes Curriculum)
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Obesity and aging are factors related to the development of chronic diseases of high incidence in current societies, such as insulin resistance, dyslipidemias and cardiovascular diseases. Recent studies have shown that obesity is characterized by increased cell senescence, in addition to adipose tissue remodeling and metabolic dysfunction. Previous studies of our group have demonstrated t…
In order to better understand the previously described interaction between the renin angiotensin system (RAS), specifically the angiotensin II receptor type 1 (AT1R), and the effects of thyroid hormone (T3) administration in cardiac muscle cells, this study proposes the analysis of receptor internalization - an important mechanism of signal transduction regulation. The ²-arrestins (²ARRs)…
Due to their high level of differentiation, the cardiac muscle cells are not able to undergo the cell division process. In this sense, the cardiomyocytes developed mechanisms of adaptation in response to changes in the homeostasis of cardiac tissue, being the regulation of the cell size the main mechanism of cytoprotection for this cell type. Intracellular signaling pathways associated to…
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| 4 / 4 | Completed scholarships in Brazil |
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