CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus São Paulo. Escola Paulista de Medicina (EPM) (Institutional affiliation for the last research proposal) Birthplace: Brazil
bachelor's at Medicina from Universidade do Estado do Rio de Janeiro (1987), master's at Microbiology from Universidade Federal do Rio de Janeiro (1995) and doctorate at Microbiology from Universidade Federal do Rio de Janeiro (1998). Has experience in Genetics, focusing on Mutagenesis, acting on the following subjects: hiv-1, variabilidade genética, hiv-1 subtypes, taxa mutacional and cultivo celular. (Source: Lattes Curriculum)
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This research proposal consists of a "spin-off" project based on volunteer samples of the Oxford-UNIFESP ChAdOx1 nCoV-19 vaccine trial. The proposal will involve the 1,000 volunteer samples, and corresponding time points, to primarily establish a repository for the whole academic community of the São Paulo State. This repository will be converted in a Biobank after the project is conclude…
In Brazil, data released by the ONU (United Nations Union) recently highlighted that there are 734,000 people infected with HIV and only in 2014 there were a number of 44,000 new infections. Even with all the government support, the number of infected people is increasing, especially in the younger population. The viral latency is the one of the factors that prevents the elimination of HI…
Epigenetic mechanisms involve a number of changes in chromatin, such as DNA methylation and histone modifications that together with the chromatin remodeling complexes, nuclear architecture and non-coding RNA define the structure of chromatin and its transcriptional activity that culminates in the alteration of gene expression profile of the cell without changes in DNA sequence. It is bel…
(Only some records are available in English at this moment)
This research proposal consists of a "spin-off" project based on volunteer samples of the Oxford-UNIFESP ChAdOx1 nCoV-19 vaccine trial. The proposal will involve the 1,000 volunteer samples, and corresponding time points, to primarily establish a collection of samples for the whole academic community of the São Paulo State. This collection will be stored in the Biobank stablished at UNIFE…
This proposal is part of the ongoing FAPESP thematic project (20/08943-5). The PD fellow will work directly on subprojects 3 and 5 described below. The thematic project consists of the unfolding of the international project with 2,000 samples of volunteers from the Oxford-UNIFESP test of the ChAdOx1 nCoV-19 vaccine. The objective is to establish a repository for the entire academic commun…
HIV is the causative agent of AIDS and is responsible for infecting mainly cells of the immune system, with emphasis on TCD4+ lymphocytes. According to UNAIDS, in 2017, 36,9 million people are infected with HIV in the world. Currently, based on previous studies, it is known that HIV-1 is influenced by the epigenetics of the host cell. The study of how the virus and its proteins may be aff…
The eradication of HIV virus from infected patients is arduous since HIV is capable of establish viral reservoirs. When the integration of the viral genetic material is made at genome regions of host cells that transcription is inactive, viral products have not enough expression to be target by antiretroviral therapy and to be detected by host Immunology System. According to that, infecti…
(Only some records are available in English at this moment)
| 1 / 1 | Ongoing research grants |
| 10 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 19 / 13 | Completed scholarships in Brazil |
| 32 / 22 | All research grants and scholarships |
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