CV Lattes
Universidade Estadual de Campinas (UNICAMP). Instituto de Química (IQ) (Institutional affiliation for the last research proposal) Birthplace: Estados Unidos
David Zachary Mokry in research grants and scholarships supported by FAPESP.
The maintenance of protein homeostasis is critical for cellular survival, and molecular chaperones are essential for this process. One important protein for facilitating refolding is Hsp90, which also has key roles in a host of other cellular functions, such as proteostasis, epigenetics, telomere maintenance, innate immunity, and biological signaling, among others. Hence, disruption of Hs…
The proper structure of proteins is maintained by a sophisticated system of proteinchaperones. When this system is disrupted, proteins can become unfolded, lose function,and form toxic aggregates that are implicated in a number of different pathologies. Theseaggregates can be eliminated by specialized chaperones that contain a disaggregaseactivity working in conjunction with an Hsp70 syst…
| 3 / 2 | Completed scholarships in Brazil |
| Associated processes | |
(References retrieved automatically from Web of Science and SciELO through information on FAPESP grants and their corresponding numbers as mentioned in the publications by the authors)
| Publications | None |
| Citations | None |
| Cit./Article | None |
| Data from Web of Science | |