CV Lattes
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Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bachelor's at Farmácia e Bioquímica from Universidade de São Paulo (2008), Master's degree in Pharmacology from the University of São Paulo (2013) and a PhD in Pharmacology from the University of São Paulo (2018). Currently Post-Doc in the Department of Pharmacology at the University of São Paulo. (Source: Lattes Curriculum)
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Several neurological conditions are associated with the blood-brain barrier (BBB) rupture, including neurodegenerative diseases, trauma, brain tumors, stroke, and epilepsy. Among the risk factors for these diseases are chronic inflammation and stress, also related to the BBB loss of integrity. Glucocorticoids (GCs) are the main hormones related to the stress response in addition of being …
The excessive inflammation can be detrimental and can lead to dysfunction and tissue damage, as seen in some diseases such as Alzheimer's and multiple sclerosis. Although glucocorticoids (GCs) are the most commonly worldwide prescribed anti-inflammatory drug, it was shown that increased levels of this hormone can enhance some aspects of inflammation, i.e., LPS (lipopolysaccharide)-induced…
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