CV Lattes
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Universidade Federal de São Carlos (UFSCAR). Centro de Ciências Exatas e de Tecnologia (CCET) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Has a bachelor's in Chemical Engineering from State University of Campinas (1985), master's in Food Engineering from State University of Campinas (1992) and PhD in Chemical Engineering from Technical University of Denmark (1998). As a lecturer of the Chemical Engineering Department of São Carlos Federal University since 1989, she has experience in the Chemical Engineering area, focusing on Biochemical Engineering, acting on the following subjects: vaccines production; recombinant protein production on E. coli cultures; studies of metabolism and physiology of E. coli and S. typhimurium; live bacterial vectors; use of agriculture wastes for 1st and 2nd generation ethanol production. She was president of the UFSCar Internal Biosafety Commission from 2012 to 2015. (Source: Lattes Curriculum)
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The bacterium Escherichia coli is one of the main hosts employed for recombinant protein production, with a turnover of E50-60 billion in the biopharmaceutical world market. Its choice as microbial cell factorial is due to the widespread knowledge accumulated about the genetics and metabolism of E. coli, the availability of fast and precise methods to modify its genome and the ease for ob…
The exploitation of biomass hemicellulosic fraction is important to economically enable the industrial production of second generation bioethanol (2G). Wild strains of Saccharomyces cerevisiae do not metabolize xylose, but recombinant strains, capable of efficiently assimilate this sugar under fermentative conditions, are available. However, the implementation of an industrial process to …
The usage of PspA antigenic protein, from S. pneumoniae surface, as a carrier protein can enhance the immunization capacity of the conjugated vaccine employed in the prevention of diseases caused by this bacterium. The cloning of this protein in E. coli enables its obtainment in large quantities. However, the production of heterologous proteins leads to stress, which can cause cell differ…
Streptococcus pneumoniae is a gram-positive bacterium, causative agent of many diseases, such as pneumonia, otitis and sinusitis. Vaccination is the most effective means of preventing infections caused by this bacterium, being the conjugated vaccine, in which the capsular polysaccharide (PS), main bacterial virulence factor, is covalently bonded to a carrier protein, the more recommended.…
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