CV Lattes
Universidade de São Paulo (USP). Instituto de Ciências Biomédicas (ICB) (Institutional affiliation from the last research proposal) Birthplace: Brazil
PhD (2019) and MSc (2014) in Immunology at the University of Sao Paulo. Graduated in Molecular Sciences (2012) at University of São Paulo, an interdisciplinary undergraduate course that is focused on the formation of scientists. She has experience in the area of Immunology, with emphasis on Tumor Immunology, acting on the following topics: dendritic cells, dendritic-tumor cell hybrid, cellular immunology, tumor immunology and tumor immunotherapy. (Source: Lattes Curriculum)
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Tumorigenesis is accompanied by the accumulation of mutations and aberrant expression of various proteins by the transformed cells, which are recognized as tumor-associated antigens (TAAs) by the adaptive immune response. However, high affinity T cells that would recognize TAAs, supposedly, should have been eliminated by the central tolerance, as these antigens are very similar or even id…
Dendritic cells (DCs) are powerful antigen-presenting cells and, since the possibility of their in vitro generation from monocytes was described, many DC-based immunotherapy protocols have been developed, including for cancer. The loading of DCs with tumor antigens can be accomplished in different ways. One method that has been widely used is the fusion of dendritic cells with tumor cells…
It is well known that, sometimes, the adaptive immune response is able to specifically recognize and eliminate tumor cells, a characteristic that has been exploited in the development of immunotherapeutic protocols. This is only possible because, during the tumorigenesis, transformed cells accumulate changes in protein sequence (mutations) and expression pattern, generating tumor-associat…
Dendritic cells (DCs) are professional antigen presenting cells highly used in immunotherapy protocols since their generation in vitro from monocytes was described. To induce antitumor responses, DCs need to be loaded with tumor antigens. Due to the tumor heterogeneity, it is preferable to load DCs with a pool of antigens, a process that can be reached by using tumor cell products. One wa…
| 3 / 3 | Completed scholarships in Brazil |
| 2 / 2 | Completed scholarships abroad |
| 5 / 5 | All Scholarships |
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