CV Lattes
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Universidade Federal de São Paulo (UNIFESP). Campus Diadema. Instituto de Ciências Ambientais, Químicas e Farmacêuticas (ICAQF) (Institutional affiliation from the last research proposal) Birthplace: Brazil
graduate at Bacharel em Ciências Biológicas from Universidade de Santo Amaro (1992), graduate at Licenciatura Em Ciências Biológicas from Universidade de Santo Amaro (1992) and ph.d. at Pharmacology from Universidade Estadual de Campinas (2006). Has experience in Immunology, acting on the following subjects: asthma, bradykinin, airway inflammation, endothelin and nitric oxide. (Source: Lattes Curriculum)
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In previous work, our group demonstrated that global intrauterine malnutrition led, in 12-week-old Wistar rats, to hypocellularity in the bone marrow and peripheral blood, a reduction in the expression of adhesion molecules and a reduction in the migration of leukocytes in these animals. In this same model, we also observed a reduction in the acute and allergic pulmonary inflammatory resp…
The maternal food restriction during gestation impair the fetal development and exposes the fetus to high levels of corticosterone, programming the development of diseases in adult life. The exposition to high levels of maternal corticosterone is related to HPA axis dysregulation and changes in morphology also lung function of offspring. Considering the epigenetic mechanisms are crucial f…
It has been demonstrated that adverse environmental factors in prenatal period can disrupt the normal pattern of fetal growth and development, leading to a phenotype more susceptible to diseases, such as hypertension, glucose intolerance, insulin resistance, hyperlipidemia, hyperinsulinemia, obesity, chronic obstructive pulmonary disease, in adulthood. In fact, failure of the maternal-pla…
(Only some records are available in English at this moment)
It has been extensively demonstrated that the failure of the maternal-placental supply to meet the nutritional needs of the fetus leads to a series of fetal adaptations, which can induce permanent changes in body structure and metabolism. Although these adaptations are beneficial in the short term, the permanent changes they cause can predispose the individual to develop diseases in adult…
Crohn's disease and ulcerative colitis are the most common forms of inflammatory human intestinal disease, being chronic pathologies that affect individuals throughout life. The genetic factor is identified as the main responsible for intestinal inflammation, linked to environmental conditions, immune system dysregulation and interaction with the intestinal microbiota. The most common man…
Crohn's disease and ulcerative colitis are the most common forms of inflammatory human intestinal disease, being chronic pathologies that affect individuals throughout life. The genetic factor is identified as the main responsible for intestinal inflammation, linked to environmental conditions, immune system dysregulation and interaction with the intestinal microbiota. The most common man…
Food restriction during gestation may prejudice the fetal growth and exposes the fetus to high maternal glucocorticoid concentrations, which may alters the development and program different disorders that present in adult life. Although data in literature showing the relashionship between maternal glucocorticoids exposure and dysregulation of HPA axis, with consequent hypercorticosterolem…
Undernourishment during pregnancy may affect fetal development and impair the maturation of the immune system, exerting prolonged negative effect on the immune response. Although these adaptations are beneficial in the short term, the permanent changes they cause can lead to adulthood diseases such as hypertension, glucose intolerance, insulin resistance, hyperlipidemia, hyperinsulinemia,…
| 1 / 1 | Ongoing grants |
| 7 / 6 | Completed research grants |
| 2 / 2 | Ongoing scholarships in Brazil |
| 6 / 3 | Completed scholarships in Brazil |
| 16 / 12 | All research grants and scholarships |
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