CV Lattes
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Sociedade Beneficente Israelita Brasileira Albert Einstein (SBIBAE). Instituto Israelita de Ensino e Pesquisa Albert Einstein (IIEPAE) (Institutional affiliation from the last research proposal) Birthplace: Brazil
Bruna Zampieri holds a degree in Biological Sciences from São Paulo State University (UNESP), São José do Rio Preto campus (2006), a Masters (2009), and a Ph.D. (2014) in Health Sciences from the Faculty of Medicine of São José do Rio Preto (FAMERP). She completed a sandwich Ph.D. program (PDSE/CAPES) at the University of Colorado Denver and Case Western Reserve University (USA), where she also conducted her postdoctoral research (20142018). From 2019 to 2024, she was a Young Investigator Fellow, and she is currently a Research Scientist in the Department of Genetics and Evolutionary Biology at the Institute of Biosciences, University of São Paulo (USP). Her research focuses on neurobiological alterations associated with Down syndrome, using iPSCs and astrocyte-derived extracellular vesicles, and is supported by national and international funding. She also collaborates on international initiatives such as the Human Trisome Project-LATAM (NIH-funded) and, since 2024, serves as a member of the Preclinical Committee of the Trisomy 21 Research Society (T21RS).Email: bruna.zampieri@ib.usp.br (Source: Lattes Curriculum)
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Down syndrome (DS), which is the consequence of the trisomy of chromosome 21 (T21), has an approximate incidence of 1:660 live births. DS is the most prevalent cause of intellectual disability of genetic origin and results in general cognitive impairment, which is typically in the mild-to-moderate range. Although DS has been known for over 160 years, our knowledge regarding the mechanisms…
Down syndrome (DS), also known as trisomy 21 (T21), which involves the presence of an extra copy of human chromosome 21 (HSA21), is the most common autosomal aneuploidy in live births. Intellectual disability is present in 100% of individuals, many of whom continue to experience learning and memory impairments and a higher risk of developing a neuropathology indistinguishable from Azheime…
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