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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

An overview of seventy years of research (1944-2014) on toxoplasmosis in Colombia, South America

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Author(s):
Alberto Canon-Franco, William [1, 2] ; Lopez-Orozco, Natalia [1] ; Enrique Gomez-Marin, Jorge [3] ; Dubey, Jitender P. [4]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Dept Med Vet Prevent & Saude Anim, BR-05508 Sao Paulo - Brazil
[2] Univ Caldas, Fac Ciencias Agr, Dept Salud Anim, Lab Parasitol Vet, Manizales - Colombia
[3] Univ Quindio, Ctr Invest Biomed, Grp Estud Parasitol Mol GEPAMOL, Armenia, Quindio - Colombia
[4] USDA ARS, Beltsville Agr Res Ctr, Anim Parasit Dis Lab, Beltsville, MD 20705 - USA
Total Affiliations: 4
Document type: Review article
Source: PARASITES & VECTORS; v. 7, SEP 4 2014.
Web of Science Citations: 14
Abstract

This paper summarizes prevalence of Toxoplasma gondii in humans and animals and associated correlates of infection, clinical spectrum of disease in humans, and genetic diversity of T. gondii isolates from Colombia. Recent studies, especially in the states of Antioquia, Quindio and Cundinamarca, indicate that toxoplasmosis is a major public health problem. Approximately half of the women of child bearing age have T. gondii antibodies, and the clinical disease in congenitally infected children is more severe than in Europe. Limited studies indicate that the strains of T. gondii from Colombia are genetically and phenotypically different than in Europe and North America. However, epidemiological factors, such as the involvement of domestic and/or wild animals in transmission, the distribution of strain diversity by natural geographic regions, and the variation in risk factors between regions that are associated with human infection in Colombia, remain unknown. Areas of research for the future are outlined. This review should be of interest to biologists, veterinarians, physicians, and parasitologists. (AU)

FAPESP's process: 12/25180-9 - Ecological approach of the sylvatic cycle of Toxoplama gondii in three biomes of the State of Mato Grosso, Brazil. Evaluations of the molecular relationship prey / predator.
Grantee:William Alberto Canon Franco
Support Opportunities: Scholarships in Brazil - Post-Doctoral