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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Fowl adenovirus Group I as a causal agent of inclusion body hepatitis/hydropericardium syndrome (IBH/HPS) outbreak in brazilian broiler flocks

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Author(s):
Mettifogo, Elena [1] ; Nunez, Luis F. N. [1] ; Santander Parra, Silvana H. [1] ; Astolfi-Ferreira, Claudete S. [1] ; Piantino Ferreira, Antonio J. [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Dept Patol, Fav Med Vet & Zootecnia, BR-05508270 Sao Paulo - Brazil
Total Affiliations: 1
Document type: Journal article
Source: Pesquisa Veterinária Brasileira; v. 34, n. 8, p. 733-737, AUG 2014.
Web of Science Citations: 5
Abstract

Commercial broiler flocks from a farm located in the State of São Paulo, Brazil, presented diarrhea, depression, increased mortality and poor weight gain. Upon post-mortem examination, classical signs of Inclusion Body Hepatitis/Hydropericardium Syndrome (IBH/HPS) were observed, including enlarged pale yellow-colored livers and straw-colored liquid in the pericardial sac. In addition, gross lesions were also observed in the kidneys, pancreas, thymus, intestines and gallbladder. Samples of these organs were analyzed by PCR for the detection of the hexon gene of the Fowl Adenovirus (FAdVs) Group I. The results were positive for both flocks (A and B) assayed by PCR. The macroscopic lesions associated with the detection of FAdV Group I by PCR in several of these affected organs allowed for the identification of IBH/HPS. In fact, this is the first report in Brazil of IBH/HPS in broilers, which identifies FAdVs group I as a causal agent of the disease. These findings may contribute to the worldwide epidemiology of the adenovirus-mediated hepatitis/hydropericardium syndrome. (AU)