Cholangiocarcinoma in an American Rhea (Rhea Americana araneipes)

Author(s)

Dell'Armelina Rocha, Paulo Ricardo ^[1] ; Lopes, Leticya Lerner ^[2] ; de Arruda, Laura Peixoto ^[2] ; Pescador, Caroline Argenta ^[2] ; Sales da Cruz, Raquel Aparecida ^[3] ; Colodel, Edson Moleta ^[2]

Affiliation

^[1] UNESP, Dept Clin Cirurgia & Reprod Anim, BR-16050680 Aracatuba, SP - Brazil

^[2] Univ Fed Mato Grosso, Dept Clin Med, Cuiaba, MT - Brazil

^[3] Univ Fed Rio Grande do Sul, Lab Patol Vet, Porto Alegre, RS - Brazil

• Document type: Journal article
• Source: Ciência Rural; v. 45, n. 2, p. 284-287, FEB 2015.
• Web of Science Citations: 0

Abstract

Cholangiocarcinomas are neoplasms that originate from the bile duct epithelium. The present case described a cholangiocarcinoma in an adult female American Rhea (Rhea Americana araneipes) by means of gross, histopathology and immunohistochemistry. Irregular, firm, multifocal, yellow-white masses, measuring from 0.4 to 6cm in diameter were observed in both liver lobes. At the cut surface, multiple firm nodules filled with connective tissue were present. Microscopically, the neoplasia was composed of small, irregular, gland-like structures of neoplastic cells surrounded by connective tissue. The cells resembled epithelial cells of the hepatic biliary ducts. Neoplastic cells were positive for cytokeratin and negative for vimentin. This is the first report of a malignant fatal neoplasia in an American Rhea. (AU)

• FAPESP's process: 13/08702-4 - Encephalitozoonosis: a novel study of brain immune response and inflammatory mediators of natural and experimental disease in rabbits and mice.
• Grantee: Paulo Ricardo Dell'Armelina Rocha
• Support Opportunities: Scholarships in Brazil - Post-Doctoral