| Full text | |
| Author(s): |
Modesto, Waleska
[1]
;
Silva dos Santos, Priscila de Nazare
[1]
;
Correia, Vinicius Machado
[1]
;
Borges, Luiza
[1]
;
Bahamondes, Luis
[1]
Total Authors: 5
|
| Affiliation: | [1] Univ Estadual Campinas, UNICAMP, Natl Inst Hormones & Womens Hlth, Campinas, SP - Brazil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | EUROPEAN JOURNAL OF CONTRACEPTION AND REPRODUCTIVE HEALTH CARE; v. 20, n. 1, p. 57-63, FEB 2015. |
| Web of Science Citations: | 11 |
| Abstract | |
Background and objective Data on record regarding weight variation in depot-medroxyprogesterone acetate (DMPA) and levonorgestrel-releasing intrauterine system (LNG-IUS) users are controversial. To date, no studies have yet evaluated weight variation in DMPA and LNG-IUS users in up to ten years of use compared to non-hormonal contraceptive users. Materials and methods A retrospective study analysed weight variations in 2138 women using uninterruptedly DMPA (150 mg intramuscularly, three-monthly; n = 714), the LNGIUS (n = 701) or a copper-intrauterine device (Cu-IUD; n = 723). Results At the end of the first year of use, there was a mean weight increase of 1.3 kg, 0.7 kg and 0.2 kg among the DMPA-, LNG-IUS-and Cu-IUD users, respectively, compared to weight at baseline (p < 0.0001). After ten years of use, the mean weight had risen by 6.6 kg, 4.0 and 4.9 kg among the DMPA-, LNG-IUS-and Cu-IUD users, respectively. DMPA-users had gained more weight than LNG-IUS-(p = 0.0197) and than Cu-IUD users (p = 0.0294), with the latter two groups not differing significantly from each other in this respect (p = 0.5532). Conclusion Users of hormonal and non-hormonal contraceptive methods gained a signifi cant amount of weight over the years. DMPA users gained more weight over the treatment period of up to ten years than women fitted with either a LNG-IUS or a Cu-IUD. (AU) | |
| FAPESP's process: | 11/01554-4 - Body composition and bone mineral density in users of depot medroxyprogesterone acetate compared to CIU Tcu380A Intrauterine Device |
| Grantee: | Waleska Oliveira Modesto |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 13/03590-3 - Effectiveness and duration of use of long term contraceptives |
| Grantee: | Vinícius Machado Correia |
| Support Opportunities: | Scholarships in Brazil - Scientific Initiation |