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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

A comparison of pre and post-operative vedaprofen with ketoprofen for pain control in dogs

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Author(s):
Fantoni, Denise Tabacchi [1, 2] ; Ida, Keila Kazue [2] ; de Almeida, Thais Ingles [1] ; Ambrosio, Aline Magalhaes [1]
Total Authors: 4
Affiliation:
[1] Univ Sao Paulo, Fac Med Vet & Zootecnia, Dept Cirurgia, BR-05508270 Sao Paulo - Brazil
[2] Univ Sao Paulo, Fac Med, Lab Invest Med 8, BR-01246903 Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: BMC Veterinary Research; v. 11, FEB 7 2015.
Web of Science Citations: 2
Abstract

Background: This prospective randomized blinded clinical study aimed to investigate the potential of vedaprofen for preventive analgesia, comparing its analgesic effects with ketoprofen administered post-operatively in dogs undergoing maxillectomy or mandibulectomy. Results: Pain control was effective and rescue analgesia was not necessary in any group. Pain scores were not significantly different between groups. The respiratory rate and rectal temperature were decreased in all groups at extubation until 6 hours post-extubation compared to baseline. Cortisol and epinephrine levels were increased only at 0.5 hours after extubation in all groups compared to baseline. Conclusions: Vedaprofen did not present any preventive analgesic effect. Pre- and postoperative vedaprofen were as effective as ketoprofen for postoperative pain control. (AU)