Treatment of obstructive sleep apnea syndrome associated with stroke

Author(s)

Mello-Fujita, Luciane ^[1] ; Kim, Lenise Jihe ^[1] ; Palombini, Luciana de Oliveira ^[1] ; Rizzi, Camila ^[1] ; Tufik, Sergio ^[1] ; Andersen, Monica Levy ^[1] ; Coelho, Fernando Morgadinho ^{[1, 2]}

Affiliation

^[1] Univ Fed Sao Paulo, Dept Psicobiol, BR-04024002 Sao Paulo - Brazil

^[2] Univ Fed Sao Paulo, Dept Neurol & Neurocirurgia, BR-04024002 Sao Paulo - Brazil

• Document type: Review article
• Source: Sleep Medicine; v. 16, n. 6, p. 691-696, JUN 2015.
• Web of Science Citations: 10

Abstract

The association between sleep-disordered breathing and stroke has been a subject of increased interest and research. Obstructive sleep apnea (OSA) is an important risk factor for stroke incidence and mortality. Moreover, OSA is a common clinical outcome after stroke, directly influencing the patient's recovery. The treatment of choice for OSA is positive airway pressure (PAP) support and the PAP appliance is considered the most recommended clinical management for the treatment of patients with cardiovascular complications. However, the implementation of PAP in stroke patients remains a challenge, considering the increased frequency of motor and language impairments associated with the cerebrovascular event. In the present study, we reviewed the main findings describing the association between stroke and OSA treatment with continuous positive airway pressure. We also discussed the types of OSA treatment, the different options and indications of PAP treatment, PAP adherence and the clinical outcomes after treatment. (C) 2014 Elsevier B.V. All rights reserved. (AU)

• FAPESP's process: 13/14420-1 - The effects of sleep restriction in an animal model of ischemic brain injury
• Grantee: Lenise Jihe Kim
• Support Opportunities: Scholarships in Brazil - Master
• FAPESP's process: 98/14303-3 - Center for Sleep Studies
• Grantee: Sergio Tufik
• Support Opportunities: Research Grants - Research, Innovation and Dissemination Centers - RIDC