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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Efferent inhibition of otoacoustic emissions in preterm neonates

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Author(s):
Mamede Carvallo, Renata Mota [1] ; Gandolfi Sanches, Seisse Gabriela [2, 3] ; Ibidi, Silvia Maria [4, 5] ; Soares, Jordana Costa [3] ; Durante, Alessandra Spada [6, 7]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, FM, Speech Therapy Course, BR-09500900 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, FM, Dept Phys Therapy Speech Therapy & Occupat Therap, BR-09500900 Sao Paulo, SP - Brazil
[3] Univ Sao Paulo, FM, Rehabil Sci, BR-09500900 Sao Paulo, SP - Brazil
[4] Univ Sao Paulo, FM, BR-09500900 Sao Paulo, SP - Brazil
[5] Univ Sao Paulo, FM, Univ Hosp, Neonatol Unit, BR-09500900 Sao Paulo, SP - Brazil
[6] Santa Casa da Misericordia Sao Paulo, Sch Med Sci, Speech Therapy Course, Sao Paulo, SP - Brazil
[7] Univ Sao Paulo, FM, Expt Pathophysiol, BR-09500900 Sao Paulo, SP - Brazil
Total Affiliations: 7
Document type: Journal article
Source: Brazilian Journal of Otorhinolaryngology; v. 81, n. 5, p. 491-497, SEP-OCT 2015.
Web of Science Citations: 2
Abstract

ABSTRACT INTRODUCTION: Abnormalities in auditory function of newborns may occur not only because of preterm birth, but also from the use of medications and from diseases related to prematurity. OBJECTIVE: To analyze the inhibitory effect from stimulation of the olivocochlear efferent system on transient evoked otoacoustic emissions in preterm neonates, comparing these data with those from full-term neonates. METHODS: This was a prospective, cross-sectional, contemporary cohort study with 125 neonates, pooled into two groups: full-term (72 full-term neonates, 36 females and 36 males, born at 37-41 weeks of gestational age); and preterm (53 neonates, 28 males and 25 females, born at ≤36 weeks of gestational age, evaluated at the corrected gestational age of 37-41 weeks). Otoacoustic emissions were recorded using linear and nonlinear click-evoked stimuli, with and without contralateral stimulation. RESULTS: The inhibitory effect of the efferent pathway in otoacoustic emissions was different (p = 0.012) between groups, and a mean reduction of 1.48 dB SPL in full-term births and of 1.02 dB SPL in preterm births was observed for the non-linear click-evoked stimulus. CONCLUSION: The results suggest a reduced inhibitory effect of the olivocochlear efferent system on otoacoustic emissions in preterm neonates. (AU)