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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Antimicrobial activity of TiO2:Ag nanocrystalline heterostructures: Experimental and theoretical insights

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Author(s):
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Andre, Rafaela S. [1] ; Zamperini, Camila A. [2] ; Mima, Ewerton G. [3] ; Longo, Valeria M. [4] ; Albuquerque, Anderson R. [5, 6] ; Sambrano, Julio R. [5] ; Machado, Ana L. [3] ; Vergani, Carlos E. [3] ; Hernandes, Antonio C. [4] ; Varela, Jose A. [2] ; Longo, Elson
Total Authors: 11
Affiliation:
[1] UFSCar Univ Fed Sao Carlos, Dept Chem, BR-13565905 Sao Carlos, SP - Brazil
[2] UNESP Univ Estadual Paulista, Inst Quim, BR-14801907 Araraquara, SP - Brazil
[3] UNESP Univ Estadual Paulista, Escola Odontol Araraquara, Dept Mat Odontol & Proteses Dent, BR-14801903 Araraquara, SP - Brazil
[4] Univ Sao Paulo, Inst Fis Sao Carlos, BR-13560970 Sao Carlos, SP - Brazil
[5] UNESP Univ Estadual Paulista, Grp Modelagem & Simulacao Mol, BR-17033360 Bauru, SP - Brazil
[6] IFSetao PE, Inst Fed Educ Ciencia & Tecnol Sertao Pernambucan, Floresta, PE - Brazil
Total Affiliations: 6
Document type: Journal article
Source: Chemical Physics; v. 459, p. 87-95, SEP 28 2015.
Web of Science Citations: 11
Abstract

We report the synthesis and characterization of silver-decorated titanium dioxide (TiO2:Ag) nanoparticles, as well as a discussion of their antimicrobial activity. This material was synthesized by microwave-assisted hydrothermal treatment and characterized by complementary techniques. The minimum inhibitory concentration and minimum bactericidal/fungicidal concentration of TiO2:Ag nanoparticles against planktonic and biofilm-forming strains of methicillin-resistant Staphylococcus aureus, Candida species (spp.) and the total biofilm mass were determined. The basis of the biological activity of TiO2:Ag was investigated by electronic analysis of the material using theoretical quantum chemical calculations. In the proposed mechanism of action, the impregnated semiconductor donates electrons to the forbidden band gaps in the metal, generating point defects, with partially located electrons and holes at the surface, initiating a radical process involving the solvent and biological target. Our results suggest that this TiO2:Ag nanomaterial has potential for use in the development of new therapeutic agents. (C) 2015 Elsevier B.V. All rights reserved. (AU)

FAPESP's process: 11/24004-0 - Synthesis, characterization and antimicrobial properties of TiO2 and TiO2:Ag nanoparticle solutions and antimicrobial effect of inorganic biomaterials coated with these nanoparticles
Grantee:Ana Lucia Machado
Support type: Regular Research Grants
FAPESP's process: 11/06786-0 - Synthesis, characterization and antimicrobial properties of TiO2 and TiO2:Ag nanoparticles solutions and antimicrobial effect of biomaterials coated with TiO2 and TiO2:Ag nanoparticles
Grantee:Camila Andrade Zamperini
Support type: Scholarships in Brazil - Post-Doctorate
FAPESP's process: 13/07296-2 - CDMF - Center for the Development of Functional Materials
Grantee:Elson Longo da Silva
Support type: Research Grants - Research, Innovation and Dissemination Centers - RIDC
FAPESP's process: 11/06900-8 - Synthesis, characterization and antimicrobial properties of TiO2 and TiO2:Ag nanoparticle solutions and antimicrobial effect of inorganic biomaterials coated with these nanoparticles
Grantee:Ewerton Garcia de Oliveira Mima
Support type: Scholarships in Brazil - Post-Doctorate