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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Drug Likeness and Selective Functionalization of Quinoxalines

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Author(s):
Ferreira, Samuel R. A. [1] ; Franco, Marcia S. F. [2] ; Diniz, Evelyn M. L. P. [1, 3] ; Emery, Flavio da Silva [2] ; Clososki, Giuliano Cesar [1]
Total Authors: 5
Affiliation:
[1] Univ Sao Paulo, Nucleo Pesquisas Prod Nat & Sintet, BR-14040903 Ribeirao Preto, SP - Brazil
[2] Univ Sao Paulo, Fac Ciencias Farmaceut Ribeirao Preto, Lab Quim Heterocicl & Med, BR-14040903 Ribeirao Preto, SP - Brazil
[3] Univ Sao Paulo, Dept Quim, Fac Filosofia Ciencias & Letras Ribeirao Preto, BR-14040901 Ribeirao Preto, SP - Brazil
Total Affiliations: 3
Document type: Journal article
Source: CURRENT ORGANIC SYNTHESIS; v. 12, n. 6, p. 714-729, 2015.
Web of Science Citations: 5
Abstract

In recent years, the pharmacological potential of quinoxalines has received vast interest due to its many applications. This review centers on a critical overview of chemical diversity and physicochemical properties of bioactive quinoxaline libraries. In addition, recent strategies for obtaining structurally diverse quinoxalines using highly selective processes will be discussed. (AU)

FAPESP's process: 12/08589-0 - Directed functionalization of quinoxalines aiming the synthesis of bioactive compounds
Grantee:Samuel Remotto Alves Ferreira
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/14362-9 - New application of organozinc reagents in the synthesis of bioactive substances
Grantee:Evelyn Mirella Lopes Pina Diniz
Support type: Scholarships in Brazil - Doctorate
FAPESP's process: 12/20990-2 - Antiinfective compounds: an evolution in the medicinal chemistry of leishmanicidal tiazoles and the search for new tuberculostic agents
Grantee:Flavio da Silva Emery
Support type: Regular Research Grants
FAPESP's process: 13/04766-8 - Applycation of new organometallic reagents in the functionalization of substances of synthetic interest
Grantee:Giuliano Cesar Clososki
Support type: Regular Research Grants