| Full text | |
| Author(s): |
Juliana Martins Aguiar
[1]
;
Sheila Oliveira Silva
[2]
;
Valdir Azevedo dos Santos
[3]
;
Sueli Akemi Taniwaki
[4]
;
Tricia Maria Ferreira de Sousa Oliveira
[5]
;
Helena Lage Ferreira
[6]
;
Lara Borges Keid
[7]
;
Fábio Gregori
[8]
;
Rodrigo Martins Soares
[9]
Total Authors: 9
|
| Affiliation: | [1] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[2] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[3] Universidade de São Paulo. Departamento de Farmácia - Brasil
[4] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[5] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos - Brasil
[6] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos - Brasil
[7] Universidade de São Paulo. Faculdade de Zootecnia e Engenharia de Alimentos - Brasil
[8] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
[9] Universidade de São Paulo. Faculdade de Medicina Veterinária e Zootecnia - Brasil
Total Affiliations: 9
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Parasitologia Veterinária; v. 25, n. 2, p. 187-195, 2016-06-07. |
| Abstract | |
Abstract Giardia duodenalis is divided into eight assemblages (named A to H). Isolates of assemblage A are divided into four sub-assemblages (AI, AII, AIII and AIV). While isolates of sub-assemblage AII are almost exclusively detected in human hosts, isolates of assemblage B are encountered in a multitude of animal hosts and humans. Here, we isolated single cysts of G. duodenalis from a human stool sample and found that one of them had overlaps of assemblage AII and B alleles and an unexpectedly high number of variants of the beta-giardin (Bg) and GLORF-C4 (OrfC4) alleles. In addition, one of the Bg alleles of that cyst had a fragment of sub-assemblage AII interspersed with fragments of assemblage B, thus indicating that this allele may be a recombinant between sequences A and B. Our results are unprecedented and put a check on the statement that different assemblages of G. duodenalis represent species with different host specificities. (AU) | |
| FAPESP's process: | 11/13472-2 - Genotyping of Giardia duodenalis: detection of mixed infections and genetic recombination in samples of human origin |
| Grantee: | Juliana Martins Aguiar |
| Support Opportunities: | Scholarships in Brazil - Doctorate |