| Full text | |
| Author(s): |
Luiz Carlos de Mattos
[1]
Total Authors: 1
|
| Affiliation: | [1] Faculdade de Medicina de São José do Rio Preto - Brasil
Total Affiliations: 1
|
| Document type: | Journal article |
| Source: | Revista Brasileira de Hematologia e Hemoterapia; v. 38, n. 4, p. 331-340, 2016-12-00. |
| Abstract | |
ABSTRACT ABO, H, secretor and Lewis histo-blood system genes control the expression of part of the carbohydrate repertoire present in areas of the body occupied by microorganisms. These carbohydrates, besides having great structural diversity, act as potential receptors for pathogenic and non-pathogenic microorganisms influencing susceptibility and resistance to infection and illness. Despite the knowledge of some structural variability of these carbohydrate antigens and their polymorphic levels of expression in tissue and exocrine secretions, little is known about their biological importance and potential applications in medicine. This review highlights the structural diversity, the biological importance and potential applications of ABO, H, Lewis and secretor histo-blood carbohydrates. (AU) | |
| FAPESP's process: | 11/08075-4 - Immunogenetic markers related to Chagas disease |
| Grantee: | Luiz Carlos de Mattos |
| Support Opportunities: | Regular Research Grants |
| FAPESP's process: | 09/17540-2 - Histo blood groups like risk factor for ocular toxoplasmosis |
| Grantee: | Luiz Carlos de Mattos |
| Support Opportunities: | Regular Research Grants |