Muscle fiber conduction velocity in different gait phases of early and late-stage diabetic neuropathy

Author(s)

Suda, Eneida Yuri ; Gomes, Aline A. ; Butugan, Marco Kenji ; Sacco, Isabel C. N.

• Document type: Journal article
• Source: JOURNAL OF ELECTROMYOGRAPHY AND KINESIOLOGY; v. 30, p. 263-271, OCT 2016.
• Web of Science Citations: 5

Abstract

We investigated the muscle fiber conduction velocity (MFCV) during gait phases of the lower limb muscles in individuals with various degrees of diabetic peripheral neuropathy (DPN). Forty-five patients were classified into severity degrees of DPN by a fuzzy model. The stages were absent (n = 11), mild (n = 14), moderate (n = 11) and severe (n = 9), with 10 matched healthy controls. While walking, all subjects had their sEMG (4 linear electrode arrays) recorded for tibialis anterior (TA), gastrocnemius medialis (GM), vastus lateralis (VL) and biceps femoris (BF). MFCV was calculated using a maximum likelihood algorithm with 30 ms standard deviation Gaussian windows. In general, individuals in the earlier stages of DPN showed lower MFCV of TA, GM and BF, whilst individuals with severe DPN presented higher MFCV of the same muscles. We observed that mild patients already showed lower MFCV of TA at early stance and swing, and lower MFCV of BF at swing. All diabetic groups showed a markedly reduction in MFCV of VL, irrespective of DPN. Severe patients presented higher MFCV mainly in distal muscles, TA at early and swing phases and GM at propulsion and midstance. The absent group already showed MFCV of VL and GM reductions at the propulsion phase and of VL at early stance. Although MFCV changes were not as progressive as the DPN was, we clearly distinguished diabetic patients from controls, and severe patients from all others. (C) 2016 Elsevier Ltd. All rights reserved. (AU)

• FAPESP's process: 13/20813-6 - Role of muscle activity in diabetic neuropathic gait pattern: a study by dynamic simulation
• Grantee: Aline Arcanjo Gomes
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 13/06123-7 - Dynamic muscles recruitment patterns during gait using high-density EMG of diabetic patients in different severity degrees classified by a fuzzy system
• Grantee: Eneida Yuri Suda
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 11/15770-0 - Influence of diabetes progression on dynamic recruitment patterns of muscular fibers analyzed through high density electromyography
• Grantee: Marco Kenji Butugan
• Support Opportunities: Scholarships in Brazil - Master