Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients

Grecco, Marcelle; dos Santos, Viviane Cardoso; Costa Pereira, Kaline Medeiros; Coelho Andrade, Luis Eduardo; da Silva, Neusa Pereira

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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Fc gamma receptor IIIa polymorphism is not associated with susceptibility to systemic lupus erythematosus in Brazilian patients

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Author(s):	Grecco, Marcelle ; dos Santos, Viviane Cardoso ; Costa Pereira, Kaline Medeiros ; Coelho Andrade, Luis Eduardo ; da Silva, Neusa Pereira Total Authors: 5
Document type:	Journal article
Source:	Revista Brasileira de Reumatologia; v. 56, n. 6, p. 515-520, NOV-DEC 2016.
Web of Science Citations:	1
Abstract
We evaluated the possible association between FCGR3AV/F (158) polymorphism and SLE susceptibility and clinical phenotype in 305 sequentially retrieved SLE patients and 300 healthy controls from the southeastern part of Brazil by allele-specific polymerise chain reaction. Our results showed no association between FCGR3A 158V/F alleles and susceptibility to SLE in this series of patients albeit the heterozygous genotype was strongly associated with the disease. (C) 2016 Published by Elsevier Editora Ltda. (AU)

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