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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Synthesis of Stannyl-Substituted D-Glucal Derivatives via Palladium-Catalyzed Regioselective Hydrostannation and Their Synthetic Applications

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Author(s):
Shamim, Anwar ; Barbeiro, Criatiane S. ; Ali, Bakhat ; Stefani, Helio A.
Total Authors: 4
Document type: Journal article
Source: CHEMISTRYSELECT; v. 1, n. 18, p. 5653-5659, NOV 1 2016.
Web of Science Citations: 6
Abstract

Stannyl derivatives of 2-alkenyl acetylated D-glucals have been synthesized via palladium-catalyzed regioselective hydrostannation in good yields under mild reaction conditions. Factors affecting the regioselectivity of hydrostannation including chelation by the neighbouring acetyl-oxygen and the electronic effect of the substituent R on alkyne have been evaluated. The synthetic applications of these stannyl derivatives of D-glucal are shown by performing Stille and Sonogashira cross-coupling reactions to obtain a library of substituted 2-alkenyl derivatives of D-glucal. (AU)

FAPESP's process: 12/00424-2 - Synthesis of small libraries using potassium Organotrifluoroborates in Suzuki-Miyaura reactions
Grantee:Helio Alexandre Stefani
Support Opportunities: Research Projects - Thematic Grants
FAPESP's process: 12/17954-4 - Cyclization reaction of Acetyl- and Ethylpyrrolidin-2-one with Potassium Organotrifluoroborate Salts
Grantee:Bakhat Ali
Support Opportunities: Scholarships in Brazil - Post-Doctoral