A systematic review of health economic evaluations of vaccines in Brazil

Author(s)

Christovam Sartori, Ana Marli ; Rozman, Luciana Martins ; Decimoni, Tassia Cristina ; Leandro, Roseli ; Dutilh Novaes, Hillegonda Maria ; de Soarez, Patricia Coelho

• Document type: Review article
• Source: HUMAN VACCINES & IMMUNOTHERAPEUTICS; v. 13, n. 6, p. 1454-1465, 2017.
• Web of Science Citations: 0

Abstract

Background: In Brazil, since 2005, the Ministry of Health requires Health Economic Evaluation (HEE) of vaccines for introduction into the National Immunization Program.Objectives: To describe and analyze the full HEE on vaccines conducted in Brazil from 1980 to 2013.Methods: Systematic review of the literature. We searched multiple databases. Two researchers independently selected the studies and extracted the data. The methodological quality of individual studies was evaluated using CHEERS items.Results: Twenty studies were reviewed. The most evaluated vaccines were pneumococcal (25%) and HPV (15%). The most used types of HEE were cost-effectiveness analysis (45%) and cost-utility analysis (20%). The research question and compared strategies were stated in all 20 studies and the target population was clear in 95%. Nevertheless, many studies did not inform the perspective of analysis or data sources.Conclusions: HEE of vaccines in Brazil has increased since 2008. However, the studies still have methodological deficiencies. (AU)

• FAPESP's process: 12/22126-3 - Systematic review of economic evaluation studies developed in Brazil from 1980-2012
• Grantee: Patricia Coelho de Soárez
• Support Opportunities: Regular Research Grants