Advanced search
Start date
Betweenand
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Suzuki-Miyaura Cross-Coupling Reaction Catalyzed by Palladium Complexes of Hydroxynaphthalene-2-Oxazolines

Full text
Author(s):
Barbeiro, Cristiane S. ; Vasconcelos, Stanley N. S. ; de Oliveira, Isadora M. ; Zukerman-Schpector, Julio ; Caracelli, Ignez ; Maganhi, Stella H. ; Stefani, Helio A.
Total Authors: 7
Document type: Journal article
Source: CHEMISTRYSELECT; v. 2, n. 26, p. 8173-8177, SEP 11 2017.
Web of Science Citations: 3
Abstract

A new palladium catalyst system, generated in situ from palladium(II) chloride and hydroxynaphthalene-2-oxazolines as ligands, has been developed and used in Suzuki-Miyaura cross-coupling reactions with potassium heteroaryl- and aryltrifluoroborate salts to synthesize biphenyl derivatives in good to high yields. It was observed that the catalyst works only when generated in situ. When isolated the formation of a solid occurs which when subjected to x-ray diffraction shows that the palladium atom is bound to two oxazolines. The presence of electron donor or electron withdrawals groups does not significantly affect reaction performance. This allows easy preparation for use without the inconvenience of catalyst decomposition and need for storage care. A plausible mechanism reaction was suggested based on HRMS studies. (AU)

FAPESP's process: 13/17960-7 - Functionalization of 3-iodo-(L)-Tyrosine via Suzuki-Miyaura Reaction Using Potassium Organotrifluoroborate salts
Grantee:Stanley Nunes Siqueira Vasconcelos
Support Opportunities: Scholarships in Brazil - Doctorate
FAPESP's process: 16/04289-3 - Synthesis of calcogeno amino acids derivatives and 4-calcogeno quinolines via multicomponent reactions
Grantee:Isadora Maria de Oliveira
Support Opportunities: Scholarships in Brazil - Doctorate (Direct)