| Full text | |
| Author(s): |
Barbeiro, Cristiane S.
;
Vasconcelos, Stanley N. S.
;
de Oliveira, Isadora M.
;
Zukerman-Schpector, Julio
;
Caracelli, Ignez
;
Maganhi, Stella H.
;
Stefani, Helio A.
Total Authors: 7
|
| Document type: | Journal article |
| Source: | CHEMISTRYSELECT; v. 2, n. 26, p. 8173-8177, SEP 11 2017. |
| Web of Science Citations: | 3 |
| Abstract | |
A new palladium catalyst system, generated in situ from palladium(II) chloride and hydroxynaphthalene-2-oxazolines as ligands, has been developed and used in Suzuki-Miyaura cross-coupling reactions with potassium heteroaryl- and aryltrifluoroborate salts to synthesize biphenyl derivatives in good to high yields. It was observed that the catalyst works only when generated in situ. When isolated the formation of a solid occurs which when subjected to x-ray diffraction shows that the palladium atom is bound to two oxazolines. The presence of electron donor or electron withdrawals groups does not significantly affect reaction performance. This allows easy preparation for use without the inconvenience of catalyst decomposition and need for storage care. A plausible mechanism reaction was suggested based on HRMS studies. (AU) | |
| FAPESP's process: | 13/17960-7 - Functionalization of 3-iodo-(L)-Tyrosine via Suzuki-Miyaura Reaction Using Potassium Organotrifluoroborate salts |
| Grantee: | Stanley Nunes Siqueira Vasconcelos |
| Support Opportunities: | Scholarships in Brazil - Doctorate |
| FAPESP's process: | 16/04289-3 - Synthesis of calcogeno amino acids derivatives and 4-calcogeno quinolines via multicomponent reactions |
| Grantee: | Isadora Maria de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Doctorate (Direct) |