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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Differentiating Leber Hereditary Optic Neuropathy from Normal-Tension Glaucoma

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Author(s):
Silveira Souto, Fernanda Maria [1] ; Cabral de Vasconcellos, Jose Paulo [1] ; de Melo, Monica Barbosa [2] ; Sartorato, Edi Lucia [2] ; Moura, Frederico Castelo [1]
Total Authors: 5
Affiliation:
[1] Univ Estadual Campinas, Fac Med Sci, Dept Ophthalmol, Tessalia Vieira de Camargo St 126, BR-01239040 Campinas, SP - Brazil
[2] Univ Estadual Campinas, Ctr Mol Biol & Genet Engn, Campinas, SP - Brazil
Total Affiliations: 2
Document type: Journal article
Source: NEURO-OPHTHALMOLOGY; v. 41, n. 2, p. 99-102, 2017.
Web of Science Citations: 0
Abstract

Glaucoma Is a neurodegenerative disorder characterized by thinning of neuroretinal rim, enlarged cup-to-disc ratio (CDR) and visual field damage. Although raised Intraocular pressure Is main risk factor for development of glaucoma, it can occur with consistently normal measurements in the Intraocular pressure as normal tension glaucoma (NTG). Enlargement of CDR is a classical sign of glaucoma, but It can also result from non-glaucomatous optic neuropathies such as Leber hereditary optic neuropathy (LHON). We describe a case of LHON with increased CDR, discuss its differential diagnosis with NTG and highlight the reasons for misdiagnoses between these two entitles. (AU)