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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

The Potential of Nanotechnology in Medically Assisted Reproduction

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Author(s):
Remiao, Mariana H. [1] ; Segatto, Natalia V. [1] ; Pohlmann, Adriana [2] ; Guterres, Silvia S. [2] ; Seixas, Fabiana K. [1] ; Collares, Tiago [1]
Total Authors: 6
Affiliation:
[1] Univ Fed Pelotas, Biotechnol Grad Program, Mol & Cellular Oncol Res Grp, Lab Canc Biotechnol, Technol Dev Ctr, Pelotas - Brazil
[2] Univ Fed Rio Grande do Sul, Postgrad Program Pharmaceut Sci, Porto Alegre, RS - Brazil
Total Affiliations: 2
Document type: Journal article
Source: FRONTIERS IN PHARMACOLOGY; v. 8, JAN 11 2018.
Web of Science Citations: 4
Abstract

Reproductive medicine is a field of science which searches for new alternatives not only to help couples achieve pregnancy and preserve fertility, but also to diagnose and treat diseases which can impair the normal operation of the reproductive tract. Assisted reproductive technology (ART) is a set of methodologies applied to cases related to infertility. Despite being highly practiced worldwide, ART presents some challenges, which still require special attention. Nanotechnology, as a tool for reproductive medicine, has been considered to help overcome some of those impairments. Over recent years, nanotechnology approaches applied to reproductive medicine have provided strategies to improve diagnosis and increase specificity and sensitivity. For in vitro embryo production, studies in non-human models have been used to deliver molecules to gametes and embryos. The exploration of nanotechnology for ART would bring great advances. In this way, experiments in non-human models to test the development and safety of new protocols using nanomaterials are very important for informing potential future employment in humans. This paper presents recent developments in nanotechnology regarding impairments still faced by ART: ovary stimulation, multiple pregnancy, and genetic disorders. New perspectives for further use of nanotechnology in reproductive medicine studies are also discussed. (AU)

FAPESP's process: 14/50928-2 - INCT 2014: Pharmaceutical Nanotechnology: a transdisciplinary approach
Grantee:Maria Vitória Lopes Badra Bentley
Support Opportunities: Research Projects - Thematic Grants