| Full text | |
| Author(s): Show less - |
Rodrigues de Oliveira, Gisele Augusto
[1, 2]
;
Morais Leme, Daniela
[2, 3]
;
de Lapuente, Joaquin
[4]
;
Brito, Lara Barroso
[1]
;
Porredon, Constanca
[4]
;
Rodrigues, Lais de Brito
[1]
;
Brull, Natalia
[4]
;
Serret, Joan Txu
[4]
;
Borras, Miquel
[5]
;
Disner, Geonildo Rodrigo
[3]
;
Cestari, Marta Margarete
[3]
;
de Oliveira, Danielle Palma
[6, 2]
Total Authors: 12
|
| Affiliation: | [1] Fed Univ Goias UFG, Fac Pharm FF, Goiania, Go - Brazil
[2] UNESP, INCT DATREM, Natl Inst Alternat Technol Detect Toxicol Evaluat, Inst Chem, POB 355, BR-14800900 Araraquara, SP - Brazil
[3] Fed Univ Parana UFPR, Dept Genet, Curitiba, Parana - Brazil
[4] Barcelona Sci Pk PCB, Unit Expt Toxicol & Ecotoxicol UTOX, Barcelona - Spain
[5] Assoc Biologists Catalonia CBC, Barcelona - Spain
[6] Univ Sao Paulo, Fac Pharmaceut Sci Ribeirao Preto FCFRP, Ribeirao Preto, SP - Brazil
Total Affiliations: 6
|
| Document type: | Journal article |
| Source: | Chemico-Biological Interactions; v. 291, p. 171-179, AUG 1 2018. |
| Web of Science Citations: | 12 |
| Abstract | |
The textile dyeing industry is one of the main sectors contributing to environmental pollution, due to the generation of large amounts of wastewater loaded with dyes (ca. 2-50% of the initial amount of dyes used in the dye baths is lost), causing severe impacts on human health and the environment. In this context, an ecotoxicity testing battery was used to assess the acute toxicity and genotoxicity of the textile dyes Direct Black 38 (DB38; azo dye) and Reactive Blue 15 (RB15; copper phthalocyanine dye) on different trophic levels. Thus these dyes were tested using the following assays: Filter paper contact test with earthworms (Eisenia foetida); seed germination and root elongation toxicity test (Cucumis sativus, Lactuca saliva and Lycopersicon esculentum); acute immobilization test (Daphnia magna and Anemia sauna); and the Comet assay with the rainbow trout gonad-2 cell fish line (RTG-2) and D. magna. Neither phytotoxicity nor significant effects on the survival of E. foetida were observed after exposure to DB38 and RB15. Both dyes were classified as relatively non-toxic to D. magna (LC50 > 100 mg/L), but DB38 was moderately toxic to A. sauna with a LC50 of 20.7 mg/L. DB38 and RB15 induced significant effects on the DNA of D. magna but only DB38 caused direct (alkaline comet assay) and oxidative (hOGG1-modified alkaline comet assay) damage to RTG-2 cells in hormetic responses. Therefore, the present results emphasize that a test battery approach of bioassays representing multiple trophic levels is fundamental in predicting the toxicity of textile dyes, aside from providing the information required to define their safe levels for living organisms in the environment. (AU) | |
| FAPESP's process: | 10/01487-2 - Toxicogenetic and ecotoxicological assessment of textile dyes |
| Grantee: | Gisele Augusto Rodrigues de Oliveira |
| Support Opportunities: | Scholarships in Brazil - Doctorate |