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(Reference retrieved automatically from SciELO through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Urinary fractional excretion of sodium, potassium and chloride in lambs supplemented with ammonium chloride to prevent urolithiasis

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Author(s):
Danilo O.L. Ferreira [1] ; Bianca P. Santarosa [2] ; Soraya R. Sacco [3] ; Priscilla F.V. Pereira [4] ; Stéfany L.O. Camilo [5] ; Júlio A.N. Lisbôa [6] ; Roberto C. Gonçalves [7]
Total Authors: 7
Affiliation:
[1] Secretaria da Agricultura e Abastecimento do Estado de São Paulo. Coordenadoria de Assistência Técnica Integral. Casa da Agricultura de Agudos - Brasil
[2] Universidade Estadual Paulista. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Clínica Veterinária - Brasil
[3] Universidade Estadual Paulista. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Clínica Veterinária - Brasil
[4] Universidade Estadual de Londrina. Centro de Ciências Agrárias. Departamento de Clínicas Veterinárias - Brasil
[5] Universidade Estadual de Londrina. Centro de Ciências Agrárias. Departamento de Clínicas Veterinárias - Brasil
[6] Universidade Estadual de Londrina. Centro de Ciências Agrárias. Departamento de Clínicas Veterinárias - Brasil
[7] Universidade Estadual Paulista. Faculdade de Medicina Veterinária e Zootecnia. Departamento de Clínica Veterinária - Brasil
Total Affiliations: 7
Document type: Journal article
Source: Pesquisa Veterinária Brasileira; v. 38, n. 5, p. 870-874, 2018-05-00.
Abstract

ABSTRACT: Urolithiasis is an important disease of lambs confined. The urine acidification, by ammonium chloride intake, is the preventive method most frequently employed. Due to the lack of specific information in sheep, this study was performed to evaluate the electrolyte changes that occur in the urine of lambs receiving ammonium chloride in the diet. One hundred male lambs, 3 months old, were kept in a feedlot during 56 days, and distributed in 3 groups: G1 (n=40) receiving 400mg/kg BW of ammonium chloride/day during 21 days; G2 (n=40) receiving 400mg/kg BW of ammonium chloride/day during 42 days; and G3 (n=20) that did not receive ammonium chloride. The lambs were examined and blood and urine samples were collected every 7 days: 0 (the beginning of ammonium chloride intake), 7, 14, 21, 28, 35, and 42 days. Serum and urine sodium (Na+), potassium (K+), chloride (Cl-), and creatinine concentrations were measured. The urinary fractional excretion (FE) of electrolytes and the urine strong ion difference [(Na+ + K+) - Cl-] were calculated. FEs of Na+, K+, and Cl- did not vary over time in G3, proving that the feedlot diet, by itself, did not influence the urinary excretion of these electrolytes. The ingestion of ammonium chloride, instead, influenced FEs over the time of feedlot. The urinary SID was more accurate than the FE of Cl- to demonstrate that the concentration of Cl- increased in the urine. It highlights the relevance of this variable. (AU)

FAPESP's process: 11/01560-4 - Clinical, laboratory and haemogasometric study of urolithiasis in sheep
Grantee:Roberto Calderon Gonçalves
Support Opportunities: Regular Research Grants
FAPESP's process: 10/19939-7 - EXPERIMENTAL MODEL OF UROLITHIASIS IN SHEEP - CLINICAL, LABORATORIAL AND HEMOGASOMETRIC STUDY
Grantee:Danilo Otávio Laurenti Ferreira
Support Opportunities: Scholarships in Brazil - Doctorate