Genomic study for maternal related traits in Santa Ines sheep breed

Author(s):Show less -

Amorim, Sabrina Thaise ^[1] ; Kluska, Sabrina ^[2] ; Berton, Mariana Piatto ^[2] ; Antunes de Lemos, Marcos Vinicius ^[2] ; Peripolli, Elisa ^[2] ; Stafuzza, Nedenia Bonvino ^[2] ; Martin, Jesus Fernandez ^[3] ; Saura Alvarez, Maria ^[3] ; Villanueva Gavina, Beatriz ^[3] ; Angel Toro, Miguel ^[4] ; Banchero, Georgget ^[4] ; Oliveira, Priscila Silva ^[5] ; Grigoletto, Lais ^[5] ; Eler, Joanir Pereira ^[5] ; Baldi, Fernando ^[2] ; Sterman Ferraz, Jose Bento ^[5]

Affiliation

^[1] Univ Fed Santa Catarina, Dept Zootecnia & Desenvolvimento Rural, Rodovia Admar Gonzaga 1346, BR-88034000 Florianopolis, SC - Brazil

^[2] Univ Estadual Paulista, Dept Zootecnia, Fac Ciencias Agr & Vet, Via Acesso Prof Paulo Donato Castellane S-No, BR-14884900 Jaboticabal, SP - Brazil

^[3] Inst Nacl Invest & Tecnol Agr & Alimentaria INIA, Crta Coruna, Km 7, 5, Madrid 28040 - Spain

^[4] INIA, Ruta 50 Km 12, Colonia - Uruguay

^[5] Univ Sao Paulo, Fac Zootecnia & Engn Alimentos, Nucleo Apoio Pesquisa Melhoramento Anim Biotecnol, Rua Duque de Caxias Norte 225, BR-13635900 Pirassununga, SP - Brazil

• Document type: Journal article
• Source: LIVESTOCK SCIENCE; v. 217, p. 76-84, NOV 2018.
• Web of Science Citations: 1

Abstract

The aim of this study was to estimate variance components and to identify genomic regions and pathways associated with maternal related traits in Santa Ines sheep breed adapted to tropical climate. Phenotypic records for maternal efficiency (ME), metabolic maternal efficiency (MME), twin lambing (TL), adult weight (AW), metabolic adult weight (MAW), and body condition score (BCS) from 1333 ewes from Santa Ines breed were used. A total of 576 animals were genotyped with the Ovine SNP12k BeadChip (Illumina, Inc.), that contains 12,785 bialleleic SNP markers. The variance components were estimated using a single trait animal model by single step genomic BLUP procedure. For AW, MAW, BCS, ME, MME and TL the mean values were 50.30 (+/- 9.76), 19.2 (+/- 2.33), 2.76 (+/- 0.72), 34.6 (+/- 15.95), 91.8 (+/- 42.52), and 1.27 (+/- 0.44), respectively. The heritabilities estimated were moderate for AW (0.32) and MAW (0.33) and low for BCS (0.04), ME (0.07), MME (0.08), and TL (0.10). A total of 7, 8, 13, 16, 19, and 09 candidate regions for ME, MME, TL, AW, MAW and BCS traits were identified, respectively. AW and MAW had a total of 15 regions in common, while AW and BCS had a common region on chromosome 21. ME and MME had six candidate regions in common, and TL had no common regions with any other features. The maternal indicator traits have genetic variability to respond to selection in Santa Ines breed, and it would be expected higher genetic gain for ewe adult weight when compared to the others studied traits. Several candidate regions related to growth, reproduction, lactation and enviromental adaptability were identified in this study. These candidate regions would give support to identify and select animals with higher maternal efficiency and fitness, and consequently, increase the productivity of Santa Ines sheep. Moreover, the results of this study should help to understand the genetic and physiologic mechanism associated with maternal related traits in Santa Ines breed. (AU)

• FAPESP's process: 11/00396-6 - Study of genetic diversity and association analysis of single nucleotide polymorphisms (SNPs) with resistance to gastrointestinal endoparasites and prolificacy of Santa Inês sheep
• Grantee: José Bento Sterman Ferraz
• Support Opportunities: Regular Research Grants
• FAPESP's process: 10/05516-7 - Study of genetic diversity and association analysis of single nucleotide polymorphisms(SNPs)with resistance to gastrointestinal endoparasites and prolificacy of sheep Santa Ines
• Grantee: Priscila Silva Oliveira
• Support Opportunities: Scholarships in Brazil - Doctorate
• FAPESP's process: 14/07566-2 - Genomics applied to ruminant production
• Grantee: José Bento Sterman Ferraz
• Support Opportunities: Research Projects - Thematic Grants