Advanced search
Start date
Betweenand
Related content
(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

Monosodium glutamate for accidental, retrospective, and medical dosimetry using electron spin resonance

Full text
Author(s):
Guidelli, Eder J. [1] ; Lima, Iara S. [1] ; Baffa, Oswaldo [1]
Total Authors: 3
Affiliation:
[1] Univ Sao Paulo, Dept Fis, Ribeirao Preto, SP - Brazil
Total Affiliations: 1
Document type: Journal article
Source: RADIATION AND ENVIRONMENTAL BIOPHYSICS; v. 57, n. 4, p. 349-356, NOV 2018.
Web of Science Citations: 1
Abstract

The risk of a radiation episode has increased in the last years due to several reasons. In case of a nuclear incident, as with the use of an improvised nuclear device, determination of the radiation doses received by the victims is of utmost importance to define the appropriate medical treatment or to monitor the late effects of radiation. Dose assessment in case of accidents can be performed using commonplace materials found in the accident area. In this paper, the dosimetric properties of monosodium glutamate are investigated by electron spin resonance spectroscopy (ESR), for retrospective and accidental dosimetry. The spectroscopic parameters were optimized to achieve higher signal intensity and better signal-to-noise ratio. As a result, the lowest detectable dose was 0.1 Gy, and monosodium glutamate showed a linear dose-response curve for doses ranging from 0.1 Gy to 10 kGy. The dosimetric signal was monitored from minutes right after irradiation, until 1 year. No changes in the signal intensity were observed over this period, meaning that doses could be assessed immediately after radiation exposure and can still be reconstructed long after the accident. This property also implies that late effects due to victim's radiation exposure could be better monitored and understood. ESR signal intensity for samples irradiated with a photon energy below 100 keV was decreased by only 27% and no dose-rate dependence was noticed. Therefore, the ability to measure doses as low as 0.1 Gy, the high stability of the dosimetric signal, as well as independence on dose rate, tissue equivalence, low-cost, and wide commercial availability make monosodium glutamate a very good dosimetric material not only for retrospective and accidental but also for medical dosimetry. (AU)

FAPESP's process: 07/06720-4 - Advances in electron spin resonance dosimetry, archeological dating and biomaterials characterization
Grantee:Oswaldo Baffa Filho
Support Opportunities: Regular Research Grants