COPD Assessment Test (CAT) is a Valid and Simple T... - BV FAPESP
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(Reference retrieved automatically from Web of Science through information on FAPESP grant and its corresponding number as mentioned in the publication by the authors.)

COPD Assessment Test (CAT) is a Valid and Simple Tool to Measure the Impact of Bronchiectasis on Affected Patients

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Author(s):
Lanza, Fernanda C. [1] ; Castro, Rejane A. S. [1] ; de Camargo, Anderson A. [1] ; Zanatta, Drielly J. M. [1] ; Rached, Samia [2] ; Athanazio, Rodrigo [2] ; Cukier, Alberto [2] ; Stelmach, Rafael [2] ; Dal Corso, Simone [1]
Total Authors: 9
Affiliation:
[1] Univ Nove Julho UNINOVE, Postgrad Program Rehabil Sci, Estado Israel St 465, Ap 23, BR-04022001 Sao Paulo, SP - Brazil
[2] Univ Sao Paulo, Fac Med, Pulm Div, Heart Inst InCor, Sao Paulo - Brazil
Total Affiliations: 2
Document type: Journal article
Source: COPD-Journal of Chronic Obstructive Pulmonary Disease; v. 15, n. 5, p. 512-519, 2018.
Web of Science Citations: 3
Abstract

The COPD assessment test (CAT) is a short questionnaire developed to help patients and clinicians to assess the impact of symptoms in routine clinical practice. We aimed to validate and to test the reproducibility of CAT in patients with bronchiectasis and correlate with the severity of dyspnea, aerobic and functional capacity, and physical activity in daily life. This is a cross-sectional study, patients with bronchiectasis underwent spirometry, cardiopulmonary exercise test (CPET), incremental shuttle walk test (ISWT), Saint George`s Respiratory Questionnaire (SGRQ), and received pedometer. CAT was applied twice (CAT-1 and CAT-2, 7 to 10 days apart). The severity of bronchiectasis was assessed by E-FACED and bronchiectasis severity index (BSI). A total of 100 patients were evaluated (48 +/- 14 years, 59 women, FVC: 67 +/- 22% pred, FEV1: 52 +/- 25% pred). According to CAT, 14% patients presented low, 40% medium, 32% high, and 14% very high impact. The higher the CAT, the worse the severity of bronchiectasis, dyspnea, quality of life, performance on the CPET, and smaller the distance walked (DW) on the ISWT and number of steps (NS) per day. There was significant correlation between CAT and SGRQ, E-FACED, BSI, NS, ISWT, oxygen uptake, and workload at CPET. CAT-1 and CAT-2 presented similar values: 21 (13-26) and 19 (13-26), respectively. The CAT is a valid and reproducible instrument in patients with bronchiectasis presenting good correlation with clinical, functional, and quality of life measurements. This easy-to-use, easy-to-understand, quick, and useful tool may play an important role to assess the impact of bronchiectasis on both daily medical practice and clinical trial settings. (AU)

FAPESP's process: 13/02851-8 - Reproducibility and validity of the Chronic Obstructive Pulmonary Disease Assessment Test (CAT) for use in adult patients with non cystic fibrosis Bronchiectasis
Grantee:Drielly Jésica Milani Zanatta
Support Opportunities: Scholarships in Brazil - Scientific Initiation