Data in support of quantitative proteomics to identify potential virulence regulators in Paracoccidioides brasiliensis isolates

Author(s)

Tashima, Alexandre Keiji ^[1] ; Castilho, Daniele Goncalves ^[2] ; Alencar Chaves, Alison Felipe ^[2] ; Xander, Patricia ^[3] ; Zelanis, Andre ^[4] ; Batista, Wagner Luiz ^{[3, 2]}

Affiliation

^[1] Univ Fed Sao Paulo, Fscola Paulista Med, Dept Bioquim, Sao Paulo, SP - Brazil

^[2] Univ Fed Sao Paulo, Fscola Paulista Med, Dept Microbiol lmunol & Parasitol, Sao Paulo, SP - Brazil

^[3] Univ Fed Sao Paulo, Dept Ciencias Biol, Diadema, SP - Brazil

^[4] Univ Fed Sao Paulo, Inst Ciencia & Tecnol, Sao Jose Dos Campos, SP - Brazil

• Document type: Journal article
• Source: DATA IN BRIEF; v. 5, p. 155-160, DEC 2015.
• Web of Science Citations: 0

Abstract

Paracoccidioides genus are the etiologic agents of para-coccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. Few virulence factors have been identified in these fungi. This paper describes support data from the quantitative proteomics of Paracoccidioides brasiliensis attenuated and virulent isolates {[}1]. The protein compositions of two isolates of the Pb18 strain showing distinct infection profiles were quantitatively assessed by stable isotopic dimethyl labeling and proteomic analysis. The mass spectrometry and the analysis dataset have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with identifier PXD000804. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (AU)

• FAPESP's process: 14/13961-1 - Role of secreted aspartyl protease (PbSAP) in virulence and dimorphism in the pathogenic fungus Paracoccidioides brasiliensis
• Grantee: Wagner Luiz Batista
• Support Opportunities: Regular Research Grants
• FAPESP's process: 12/19321-9 - Proteomic and peptidomic characterization of Brazilian spider venoms by mass spectrometry
• Grantee: Alexandre Keiji Tashima
• Support Opportunities: Regular Research Grants
• FAPESP's process: 11/14392-2 - Evaluation of the involvement of Ras GTPase from Paracoccidioides brasiliensis in thermo-dimorphism and during oxidative and nitrosative stress
• Grantee: Wagner Luiz Batista
• Support Opportunities: Regular Research Grants